SEED 2015 Program
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| Wednesday, June 10 | |
| 8:00-12:15 | Registration Check-In |
| 9:00-9:30 | Coffee served |
| 9:30-9:45 | Welcome - Dan Gibson, Synthetic Genomics |
| 9:45-10:00 | Background on Mark Ptashne |
| 10:00-12:00 |
Session 1: Systems Modelling Chair: Pam Silver, Harvard University |
| 10:00-10:30 | Georg Seelig, University of Washington - Learning the Sequence Determinants of Exon Definition from Millions of Random Synthetic Sequences |
| 10:30-11:00 | Howard Salis, Penn State - Scalable System-Wide Design of TF- and dCas9-Based Genetic Circuits |
| 11:00-11:30 | Andrea Weisse, University of Edinburgh - Quantifying Host-Circuit Interactions with a Mechanistic Chassis Model |
| 11:30-12:00 | John Fisk, Colorado State University - Biological Insights from a Computational Simulation of the M13 Bacteriophage Life Cycle |
| 12:00-2:00 | Lunch |
| 2:00-4:00 | Registration Check-In |
| 2:00-4:00 |
Session 2: Biomedical Applications Chair: Ron Weiss, MIT |
| 2:00-2:30 | Jeff Way, Wyss Institute - Spatial and Quantitative Optimization of Engineered Multi-Element Therapeutic Proteins |
| 2:30-3:00 | Kyle Cady, SGI - Engineering Bacteriophage to Address Multidrug-Resistant Pathogens |
| 3:00-3:30 | Yvonne Chen, UCLA - Engineering Smarter and Stronger T Cells for Cancer Immunotherapy |
| 3:30-4:00 | Steve Shih, JBEI - µsynth: A Versatile Microfluidic Device for Automating the Synthetic Biology Process |
| 4:00-4:30 | Coffee Break |
| 4:30-6:30 |
Session 3: Biological Circuits and Context Chair: Richard Murray, Caltech |
| 4:30-5:00 | John Dueber, UC Berkeley - Use of an enzyme-coupled biosensor to engineer a BIA fermentation pathway from glucose in Saccharomyces cerevisiae |
| 5:00-5:30 | Stanley Qi, Stanford University - CRISPR Genetic Circuits for Genome Control and Interfacing |
| 5:30-6:00 | Eric Klavins, University of Washington - Toward Synthetic Multicellular Behaviors in Yeast |
| 6:00-6:30 | Sri Kosuri, UCLA - Synthetic Approaches to Studying Cis-Regulation |
| 6:30-7:30 | Reception |
| Thursday, June 11 | |
| 7:30-12:00 | Registration Check-In |
| 8:00-8:30 | Breakfast |
| 8:30-9:30 | Keynote: Pam Silver, Harvard University - Designing Biology for a Healthy World |
| 9:30-10:00 | Coffee Break |
| 10:00-12:00 |
Session 4: Metabolism, Metabolomics and Engineering Metabolism Chair: Chris Voigt, MIT |
| 10:00-10:30 | Stephanie Culler, Genomatica - The development of platform-based technologies for the optimization of sustainably produced chemicals |
| 10:30-11:00 | Kris Prather, MIT - Metabolite Valves: Dynamic Control of Metabolic Flux for Pathway Engineering |
| 11:00-11:30 | Diego Oyarzun, Imperial College London - Gene Circuits for Self-Tuning Metabolic Pathways |
| 11:30-12:00 | Tammy Hsu, UC Berkeley - Protecting Groups for Improved Control of Indigo Biosynthesis |
| 12:00-1:30 | Lunch |
| 1:30-3:30 |
Session 5: Agriculture and Water Chair: Stephanie Culler, Genomatica |
| 1:30-2:00 | Virginia Ursin, Monsanto - What do Soybeans Have to do with Sustainable use of our Oceans? |
| 2:00-2:30 | Mary Dunlop, University of Vermont - Engineering Robust Hosts to Improve Microbial Biofuel Production |
| 2:30-3:00 | Huirong Gao, Pioneer - Targeted Integration of Genes into the Maize Genome Facilitated By Cas9-gRNA System |
| 3:00-3:30 | Coffee Break |
| 3:30-5:30 |
Session 6: Advancing Synthetic Biology Tools, Automation and Analytical Technologies Chair: Alicia Jackson, DARPA |
| 3:30-3:45 | Introduction - Alicia Jackson, DARPA |
| 3:45-4:10 | Emily Leproust, Twist Bioscience - Broadband DNA Synthesis |
| 4:10-4:35 | Ben Gordon, MIT/Broad Foundry - Rapid Prototyping of Genetic Programs |
| 4:35-5:05 | Jacob Beal, Raytheon - Synthetic Biology Open Language (SBOL): Community-Driven Standard for Communication of Synthetic Biology Designs |
| 5:05-5:30 | Ron Weiss, MIT |
| 5:30-7:00 | Poster Session A |
| Friday, June 12 | |
| 7:30-12:00 | Registration Check-In |
| 8:00-8:30 | Breakfast |
| 8:30-9:30 | Keynote: Jennifer Doudna, UC Berkeley - Re-writing Genomes: Discoveries to Applications |
| 9:30-10:00 | Coffee Break |
| 10:00-12:00 |
Session 7: DNA and RNA Based Synthetic Biology Chair: Yvonne Chen, UCLA |
| 10:00-10:30 | Erik Winfree, Caltech - Designing and verifying molecular circuits made of DNA |
| 10:30-11:00 | Rebecca Schulman, Johns Hopkins University - Powered DNA Strand Displacement Circuits for Continuous Environmental Monitoring and Memory |
| 11:00-11:30 | Shaunak Sen, Indian Institute of Technology - Design of a Toolbox of RNA Thermometers |
| 11:30-12:00 | Niles Pierce, Caltech - Dynamic RNA Nanotechnology |
| 12:00-2:00 | Lunch and NIH Mentoring Session |
| 2:00-3:00 |
Session 8: Minimal Systems Chair: Barry Canton, Ginkgo Bioworks |
| 2:00-2:30 | Elisa Franco, UC Riverside - Bottom Up Construction of Dynamic Biomolecular Materials |
| 2:30-3:00 | Michelle O'Malley, UC Santa Barbara - Reconstructing Anaerobic Microbiomes from the ‘Bottom-up': New Techniques to Decipher Interwoven Metabolism |
| 3:00-4:45 |
Student Session Chair: Barry Canton, Ginkgo Bioworks |
| 3:00-3:15 | Daniel A. Martin-Alarcon, MIT - A Modular Protein Architecture for Generalized RNA Targeting: Development and Application to RNA Monitoring, Control, and Protein Scaffolding |
| 3:15-3:30 | Thomas Prescott, Oxford - Designing Conservation Relations in Layered Synthetic Biomolecular Networks |
| 3:30-4:00 | Coffee Break |
| 4:00-4:15 | Hoang Long Pham, National University of Singapore - Directed Evolution of Acid-Tolerant Phenotype Using an Engineered pH-Riboswitch |
| 4:15-4:30 | Neda Hassanpour, Tufts - Enabling Selection in Directed Evolution of Enzymes Via Cellular Engineering |
| 4:30-4:45 | Enoch Yeung, Caltech - Quantifying and Modeling Compositional Context Effects on Synthetic Biocircuits in E. coli |
| 4:45-5:15 |
ACS Synthetic Biology Young Investigator Award Lecture Chair: Ranjini Prithviraj, ACS Synthetic Biology |
| 5:15-6:45 | Poster Session |
| 7:00- | Off site party at Ginkgo Bioworks |
| Saturday, June 13 | |
| 7:30-9:30 | Registration Check-In |
| 8:00-8:30 | Breakfast |
| 8:30-9:30 | Keynote: Martin Fussenegger, ETH Zurich - Prosthetic Gene Networks for Biomedical Applications |
| 9:30-11:00 |
Session 9: Biological Parts Chair: Jeff Way, Wyss Institute for Biologically Inspired Engineering |
| 9:30-10:00 | Caroline Ajo-Franklin, LBL - Controlling Organisms Electrically with Synthetic Biology |
| 10:00-10:30 | Stacy Anne-Morgan, UC Berkeley - Towards the High–Throughput Construction of Fluorescent Biosensors |
| 10:30-11:00 | Erik Carlson, Northwestern University - A System for Unprecedented Ribosome Engineering in Living E. coli |
| 11:00-11:30 | Coffee Break |
| 11:30-1:00 |
Session 10: Microbial Communities and Microbiome Genomics Chair: Dan Gibson, Synthetic Genomics |
| 11:30-12:00 | Giles Oldroyd, John Innes Institute - Engineering nitrogen fixing symbiotic associations in cereals |
| 12:00-12:30 | Michael Fischbach, UCSF - Insights from a global view of secondary metabolism: Small molecules from the human microbiota |
| 12:30-1:00 | Peter Nguyen, Harvard University - Synthetic Biology Engineering of Biofilms As Nanomaterials Factories |
