Technical Program | AIChE

2026 Synthetic Biology: Engineering, Evolution and Design (SEED) Technical Program* 

*Schedule subject to change as program is finalized. Check back for updates!


Start Time End Time  
June 15, 2026 All Central Daylight Time (MST)
    Day 1
8:00 AM 12:00 PM Registration + Badge Pick Up 
9:00 AM 9:15 AM Welcome Remarks by Chairs: Harris Wang, Columbia University & Peyton Greenside, BigHat Biosciences
9:15 AM 10:00 AM KEYNOTE: Hiroaki Suga, University of Tokyo, Co-founder of Peptidream
10:00 AM 10:30 AM Morning Coffee Break 
10:30 AM 11:55 AM Session 1: Cell-free Systems, Synthetic Genomes & Synthetic Cells
10:30 AM 10:35 AM Session Introduction by Session Chairs: Angad Mehta, UIUC
10:35 AM 11:00 AM Invited Speaker: Allen Henderson, Sutro Biopharma
11:00 AM 11:25 AM Invited Speaker: DNA Replication Coupled to Cell-Free Gene Expression for Accelerated In Vitro Evolution, Zhanar Abil, University of Florida
11:25 AM 11:40 AM Selected Abstract: A Self-Replicating Artificial Genome and Darwinian Evolution of a Replication Protein In Vitro Using the Bacterial Genome Replication Reconstitution System, Yuta Yamagishi, Rikkyo University
11:40 AM 11:55 AM Selected Abstract: Selective Haploidization Enables Scalable Consolidation of Synthetic Yeast Chromosomes, Alba Ballerini, NYU Langone Health
11:55 AM 12:10 PM Selected Abstract: Developing the Use of Fully Synthetic DNA for Therapeutic Production In Cell-Free Expression Systems, Katherine Rhea, U.S. Army DEVCOM Chemical Biological Center
12:10 PM 1:10 PM Lunch With A Legend
1:10 PM 2:35 PM Session 2: Nucleic Acid, Protein, Enzyme Design and Engineering 
1:10 PM 1:15 PM Session Introduction by Session Chairs: Esteban Toro, Twist Bioscience & Juan Velasquez, Merck
1:15 PM 1:40 PM Invited Speaker: Birgit Kosjek, Merck
1:40 PM 2:05 PM Invited Speaker: Julius Lucks, Northwestern University
2:05 PM 2:20 PM Selected Abstract: Growth-Based Quantitative Sequencing (GROQ-seq) of T7 RNA Polymerase Enables Large-Scale Mapping of Sequence-Function Landscape, James McLellan, The Align Foundation
2:20 PM 2:35 PM Selected Abstract: Programmable RNA Molecular Devices for Biosensing and Cellular Gene Expression Regulation, Fan Hong, University of Florida
2:35 PM 2:50 PM Selected Abstract: A Scalable Design–Build–Test Platform for Accessible Protein Discovery, Thomas Fryer, MIT
2:50 PM 3:20 PM Afternoon Coffee Break
3:20 PM 4:05 PM Panel Discussion: Funding Opportunities led by Chris Myers, University of Colorado-Boulder & Richard Murray, Caltech; Panelists: Mark Salvador, DARPA, Anthony Garza, NSF, Daria Fedyukina, ARPA-H, Stephanie McElhinny, U.S. Army Research Office, Andrea Hodgson, Schmidt SciencesJermont Chen, NIBIB & NIH
4:05 PM 4:30 PM Lightning Talks Moderated by 
4:05 PM 4:10 PM Lightning Talk: Synthetic Bacteria As Novel Mammalian Endosymbionts, Liyam Chitayat, MIT
4:10 PM 4:15 PM Lightning Talk: Mapping Context Dependency In Synthetic Biology Using Cell-Free Systems, Fernanda Piorino Macruz De Oliveira, National Institute of Standards and Technology
4:15 PM 4:20 PM Lightning Talk: Leucine Zipper Bispecifics: A Synthetically Dimerized Method to Express Multi-Chain Bispecific Antibodies In One-Pot Cfps Reaction, Wei Chan, BigHat Biosciences
4:20 PM 4:25 PM Lightning Talk: Beyond DNA Barcodes: Enzyme Screening through MS-Based Genotype Identification, Denijel Latifovic, ETH Zürich
4:25 PM 4:30 PM Lightning Talk: Developing Dynamic Biosensors for Emerging Synthetic Opioids with Computational Design, Rachel Chayer, University of Colorado Boulder
4:30 PM 4:35 PM Lightning Talk: Probing Mutability of Tev Protease through Comprehensive Deep Mutational Scanning with Groq-Seq, Svetlana Ikonomova, National Institute of Standards and Technology
4:35 PM 5:35 PM Cocktail Reception + Poster Session 1
     
Start Time End Time  
June 16, 2025 All Central Daylight Time (MST)
    Day 2
8:00 AM 12:00 PM Registration + Badge Pick Up 
9:00 AM 9:05 AM Welcome Remarks by Chair: Harris Wang, Columbia University & Peyton Greenside, BigHat Biosciences
9:05 AM 9:50 AM KEYNOTE: Reshma Shetty, Gingko Bioworks
9:50 AM 10:20 AM Morning Coffee Break 
10:20 AM 11:45 AM Session 3: New Chemicals & Materials from Synthetic Biology
10:20 AM 10:25 AM Introduction to Session by Session Chair: Colin Harvey, Hexagon Bio & Caroline Ajo-Franklin, Rice University
10:25 AM 10:50 AM Invited Speaker: A modular biosynthetic platform enabling scalable access to terpenes for diverse applications, Simone Montovani, Amyris
10:50 AM 11:15 AM Invited Speaker: Engineered living optical fibers and other bacterial photonic devices, Anne Meyer, University of Rochester
11:15 AM 11:30 AM Selected Abstract: Polyketide-Based Biosynthetic Platforms for Commodity and Specialty Chemicals, Qingyun Dan, Lawrence Berkeley National Laboratory
11:30 AM 11:45 AM Selected Abstract: Engineering Microbial Consortia for Mixed Plastic Upcycling, Tae Seok Moon, J. Craig Venter Institute
11:45 AM 12:00 PM Selected Abstract: Programmable Engineered Living Materials through CP19K-Mediated Self-Assembly, Ingrid Roselyne Dukundane, University of Maryland College Park
12:00 PM 1:00 PM Lunch
1:00 PM 2:25 PM Session 4: Living Medicines and Therapeutics
1:00 PM 1:05 PM Introduction by Session Chair: Shujun Yuan, Outpace bio & Angad Mehta, UIUC
1:05 PM 1:30 PM Invited Speaker: Sensitive and multispecific targeting of cancer with the Chimeric TCR platform, Sylvain Simon, Fred Hutch
1:30 PM 1:55 PM Invited Speaker: Andrew Ng, Genentech
1:55 PM 2:10 PM Selected Abstract: Surface Expression of Antitoxin on Engineered Bacteria Neutralizes Genotoxic Colibactin In the Gut, Jiahe Li, University of Michigan
2:10 PM 2:25 PM Selected Abstract:Designing Probiotics to Suppress Pseudomonas Aeruginosa Via Metabolic Niche Exclusion, Jacob Hilzinger, University of California, Berkeley
2:25 PM 2:40 PM Selected Abstract: Engineered Protein Circuits for Cancer Therapy, Andrew Lu, California Institute of Technology
2:40 PM 3:10 PM Afternoon Coffee Break
3:10 PM 3:55 PM Panel Discussion: Biosafety and Biosecurity in the Era of AI led by Harris Wang, Columbia University & Sam Weiss Evans, Federation of American Scientist; Panelists: Kevin Flyanolts, Aclid, James Diggans, Twist Bioscience, Jaime Yassif, Nuclear Threat Initiative, & Geoffrey Taghon, AI Engineering for Bioscience @ JHU + NIST
3:55 PM 4:25 PM Lightning Talks Moderated By 
3:55 PM 4:00 PM Lightning Talk: Microbial Metabolism-Mediated Carbene Transfer, Alexis Holwerda, The University of Texas at Austin
4:00 PM 4:05 PM Lightning Talk: Engineering Bacterial Multicellular Structures for Therapeutic Applications, Varunaa Sri Hemanth Kumar, UMD
4:05 PM 4:10 PM Lightning Talk: Accelerated Design of Engineered Living Wood Composite Materials,Wilfried Weber, INM - Leibniz Institute for New Materials
4:10 PM 4:15 PM Lightning Talk: From Pathogen to Platform: Engineering Cryptococcus Neoformans As a Living Biomaterial for Therapeutic Delivery to the Brain, Clinton Smith, University of Florida
4:15 PM 4:20 PM Lightning Talk: Domesticating Brucella Melitensis Dvjbr for Living Bacterial Immunotherapy, Chelsea Hu, Texas A&M University
4:20 PM 4:25 PM Lightning Talk: Unlocking Potent Anti-Tumor Immune Response Via CRISPR-Mediated Deletion of Immunosuppressive Effectors In Salmonella Cancer Therapy, Chinmay Deshpande, University of Massachusetts Amherst
4:25 PM 5:25 PM Poster Session 2
     
Start Time End Time  
June 17, 2026 All Central Daylight Time (MST)
    Day 3
8:00 AM 12:00 PM Registration + Badge Pick Up 
9:00 AM 9:05 AM Welcome Remarks by Chair:  Harris Wang, Columbia University & Peyton Greenside, BigHat Biosciences
9:05 AM 9:50 AM KEYNOTE: Evolutionary design from molecular to genome scale, Brian Hie, Stanford University
9:50 AM 10:20 AM Morning Coffee Break 
10:20 AM 11:45 AM Session 5: Foundational ML Models for Biology
10:20 AM 10:25 AM Session Introduction by Session Chairs: 
10:25 AM 10:50 AM Invited Speaker: From Sequence and Structure to Function: AI-Guided Protein Evolution, Kaiyi Jiang, Princeton University
10:50 AM 11:15 AM Invited Speaker: Raphael Townshend, Atomic AI
11:15 AM 11:30 AM Selected Abstract: What Does It Take to Build a Foundation Model for Antibody Biophysics and Developability?, Hunter Elliott, BigHat Biosciences
11:30 AM 11:45 AM Selected Abstract: Centaur: Bridging Continuous and Discrete Generation for Protein Sequence Structure Co-Design, Leo Tianlai Chen, Harvard Medical School
11:45 AM 12:00 PM Selected Abstract: Generative Design of Synthetic Gene Circuits for Functional and Evolutionary Properties, Olivia Gallup, University of Oxford
12:00 PM 1:00 PM Lunch
1:00 PM 2:25 PM Session 6: Engineered Cellular Sensors, Transducers, and Actuators
1:00 PM 1:05 PM Session Introduction by Session Chair: Caroline Ajo-Franklin, Rice University & Harris Wang, Columbia University
1:05 PM 1:30 PM Invited Speaker: Technologies to capture mammalian developmental cell trajectories, Nozomu Yachie, University of British Columbia
1:30 PM 1:55 PM Invited Speaker: Brandon Fields, Fieldstone Bio
1:55 PM 2:10 PM Selected Abstract: High-Throughput Engineering of Membrane Sugar Transporter Biosensors, Sojeong Gwon, Georgia Institute of Technology
2:10 PM 2:25 PM Selected Abstract: Bacterial Biosensors for Lung Cancer Detection, Michael Brasino, University of Vermont
2:25 PM 2:40 PM Selected Abstract: A Genetically Encoded Device for Transcriptome Storage In Mammalian Cells, Yu-Kai Chao, Broad Institute of MIT and Harvard
2:40 PM 3:10 PM Afternoon Coffee Break
3:10 PM 4:10 PM Session 7: Engineering Microbiomes, Ecosystems, and Non-Model Organisms
3:10 PM 3:15 PM Session Introduction by Session Chairs: Tim Schnabel, Switch Bioworks & Joanna Tannous, ORNL
3:15 PM 3:40 PM Invited Speaker: Nili Ostrov, Cultivarium
3:40 PM 3:55 PM Invited Speaker: Environmentally Triggered Growth-Production Programming in Undomesticated Cereal Inoculants, Tim Haskett, Switch Bioworks
3:55 PM 4:10 PM Selected Abstract: Engineering Trichoderma-Based Biosentinels: Smart Systems to Detect, Remember, and Respond to Environmental Stressors, Kyle Davis, Oak Ridge National Laboratory
4:10 PM 4:25 PM Selected Abstract: Building Synthetic Lichens through Fungal-Cyanobacterial Partnerships, Jorge Guío, Michigan State University
4:25 PM 4:40 PM Selected Abstract: Engineering Horizontal Gene Transfer As a Biocontrol Strategy for Microbial Communities, Sai Varun Aduru, University of Rochester 
4:40 PM 5:10 PM Lightining Talks Moderated By:
4:40 PM 4:45 PM Lightning Talk: Recoding Life with a 19-Amino Acid Alphabet Via Generative Modeling, Charlotte Rochereau, CUMC
4:45 PM 4:50 PM Lightning Talk: A Modular ML Approach to Design Multiplexed Whole Cell Bacterial Biosensors, Jichi Wang, Massachusetts Institute of Technology
4:50 PM 4:55 PM Lightning Talk: A Single Protein Scaffold Enables Programmable Broad-Spectrum Small-Molecule Detection, Hao Tian, University of California
4:55 PM 5:00 PM Lightning Talk: From Characterization to Prediction: A Dynamic and Single-Cell Framework for Context-Aware Biosensor Design, Mara Pisani, Institute for Integrative Systems Biology, (UV-CSIC) Spanish National Research Council
5:00 PM 5:05 PM Lightning Talk: A Synthetic Biology Platform for Engineering Self Sustaining and Permanent Bioluminescence In Multicellular Plant Systems, Minseo Kim, Korea Science Academy of KAIST
5:05 PM 5:10 PM Lightning Talk: Enabling Host-Informed Microbiome Engineering through Non-Invasive Longitudinal Host Transcriptomic Profiling, Yiwei Sun, Columbia University
5:10 PM 6:10 PM Poster Session 3
     
Start Time End Time  
June 18, 2026 All Central Daylight Time (MST)
    Day 4
8:00 AM 12:00 PM Registration + Badge Pick Up 
9:00 AM 9:05 AM Welcome Remarks by Chairs: Harris Wang, Columbia University & Peyton Greenside, BigHat Biosciences
9:05 AM 9:50 AM KEYNOTE: George Church, Harvard Medical School and MIT
9:50 AM 10:20 AM ACS SynBio Young Innovator Award: Xiaojing Gao, Stanford University
10:20 AM 10:50 AM Morning Coffee Break 
10:50 AM 12:15 PM Session 8: Bio-design Automation
10:50 AM 10:55 AM Session Intrudction by Session Chairs: Chris Myers, University of Colorado-Boulder & Harris Wang, Columbia University
10:55 AM 11:20 AM Invited Speaker: Robotic platforms unlock new approaches and applications for engineering biology, Harrison Steel, University of Oxford
11:20 AM 11:45 AM Invited Speaker: An AI-powered Self-driving Biofoundry for Synthetic Biology, Huimin Zhao, UIUC
11:45 AM 12:00 PM Selected Abstract: Emergex: A Computational Framework for Designing Emergent Dynamics In Chemical Reaction Networks, Colin Yancey, Johns Hopkins University
12:00 PM 12:15 PM Selected Abstract: Modeling Toehold-Mediated Strand Exchange Circuits across Synthetic Biology Applications, Zoila Jurado, National Institute of Standards and Technology
12:15 PM 12:30 PM Selected Abstract: SynBioSuite2: A Standards-Enabled Platform for Integrated Synthetic Biology Workflows, Gonzalo A. Vidal Peña, University of Colorado Boulder
12:30 PM 12:35 PM Lightning Talk: Multi-Variable Control to Enhance the Modularity of CRISPR Systems, Krishna Manoj, Massachusetts Institute of Technology
12:35 PM 12:40 PM Lightning Talk: Milliner Platform™: High-Speed Wet Lab and Machine Learning Integration for Bio-Design Automation, Adam Carr, BigHat Biosciences
12:40 PM 12:45 PM Lightning Talk: Bio-Design Automation for Strain Engineering, William Henson, Battelle Memorial Institute
12:45 PM 12:55 PM Closing Remarks from Chairs:  Harris Wang, Columbia University & Peyton Greenside, BigHat Biosciences